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Folic acid after methotrexate
Folic acid after methotrexate
So I only had the 1 injection of methotrexate following a pregnancy of unknown location.
I went to hospital yesterday for my day 14 bloods and discharged with the good news my hormone level was down to 1.
I was told at the injection not to try again for 3 months which I understand however I was only told yesterday NOT to take folic acid for 3 months to make sure the injection has fully worked and out of my system.
My concern is you are advised to take folic acid 3 months before ttc… is this now forcing me to wait 6 months before ttc again?
Has anyone else been told this or taken folic acid straight away after successful methotrexate/hospital discharge?
Thanks
Leanne
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Re: Folic acid after methotrexate
Sorry to hear about this. I just went through the exact same thing a few weeks ago. The midwife at Early Pregnancy phoned to tell me my HcG was below 3 and said that I could start taking folic acid from that day. I was told I could ttc 3 months from the date of injection and that I would more than likely get enough folic acid from a good diet but if I wanted to supplement before ttc, I could start from that day.
I know the Ectopic Pregnancy Trust advise to take folic acid for 12 weeks from the date of your HcG levels being down to 0 but I was told by two midwives it was from the date of injection so that’s what I’m going with.
Hope this helps!
Debbie x
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Re: Folic acid after methotrexate
I am so sorry to hear of your ectopic pregnancy loss,
I am glad to hear that your levels have reduced and you can start to plan ahead.
The advice from our medical team following Methotrexate injection remains that you should wait until your hCG levels have fallen to below 5mIU/mL (your doctor will advise you when this is through blood tests) and then take a folic acid supplement for 12 weeks before you try to conceive.
This is because the Methotrexate may have reduced the level of folate in your body which is needed to ensure a baby develops healthily. The Methotrexate is metabolised quickly but it can affect the quality of your cells, including those of your eggs and the quality of your blood for up to three months after it has been given. The medicine can also affect the way your liver works and so you need to give your body time to recover properly before a new pregnancy is considered. A shortage of folate could result in a greater chance of a baby having a neural tube defect such as hare lip, cleft palate, or even spina bifida or other NT defects. This is why the "wait" and then taking folic acid for 12 weeks before trying to conceive is so important.
We would therefore strongly recommend following this advice before trying to concieve.
Sending much love,
Karen x
The Ectopic Pregnancy Trust
Registered Charity Number: 1071811
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Re: Folic acid after methotrexate
Thanks for your post, so sorry to hear about your loss too.
Not sure why I was told to wait 3 months before taking folic acid again. I understand the not ttc but not the folic acid.
I was told the injection starts to leave your system within a couple of days of having it but the long term effect of not having the folate in your body is what is harmful to a baby if conceived in those 3 months.
My levels were down to 1 so definitely within the 5 as advised.
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Re: Folic acid after methotrexate
Yeah I feel the same. I didn’t really understand it either.
It’s such a minefield, Ive been told so many different things. On the consent form that I signed before getting the injection it said you can’t conceive within 3 months and only have to folic acid for one month before ttc. So confusing, but as Karen said if the medical research states it’s best to take folic acid for 12 weeks I’ll just follow that advice.
Re: Folic acid after methotrexate
Yeah it’s so confusing!
I don’t want to wait 3 months before taking folic acid for another 3 months before trying again.
I’ll just leave it a few days so my 1 goes down to 0.
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Re: Folic acid after methotrexate
Re: Folic acid after methotrexate
My journey following this will be very different as we have requested to go down the IVF route. I’ve lost 3 babies to miscarriage at 6 weeks in the last 15 months and then this 4th one 2 weeks ago. I’m pushing on 40 and feel like I now need the medical intervention
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Re: Folic acid after methotrexate
This is my first loss but feeling quite anxious about trying again. I’ve not long turned 30 though so still feeling hopeful x
Re: Folic acid after methotrexate
It’s natural to feel anxious about trying again. I remember the first time of intimacy after every loss we had I would cry! I’d cry so much because I couldn’t wait to try again and get pregnant, but also cry because of being scared of losing another.
Try talking to people, it helps so much! I’m sure the next time you fall pregnant the hospital will keep a close eye on you x